The average content of neutral sugar in desiccated Dendrobium officinale is up to 58.3% [26]. eCollection 2019. Tìm kiếm nhân giống invitro dendrobium officinale kimura et migo , nhan giong invitro dendrobium officinale kimura et migo tại 123doc - Thư viện trực tuyến hàng đầu Việt Nam Dendrobium officinale contains a kind of bibenzyl and a kind of phenanthrene identified in D. chrysotoxum before: chrysotobibenzyl (11) and erianin (6). However, gastric ulcer is a chronic disease, the security of long-term administration of Dendrobium officinale still uncertain. 81573700), Zhejiang Provincial Natural Science Foundation of China (no. Copyright © 2017 Hanxiao Tang et al. Hypoglycemic activity, another important property of Dendrobium officinale, has been studied a lot. National Center for Biotechnology Information, Unable to load your collection due to an error, Unable to load your delegates due to an error. Dendrobium officinale Kimura et Migo (Dendrobium catenatum Lindley), a functional food and medicine herbal, has shown great pharmacological activity on diabetes and hypertension.16) Polysaccharides, the major constituent in den - drobium species,17) were recently reported to possess various Moreover, Dendrobium officinale was used to treat Sjögren’s syndrome (SS) with dry eyes and mouth due to impaired lacrimal and salivary glands [80]. Results. A mixture of D. officinale and American ginseng has been shown to enhance cell-mediated immunity, humoral immunity, and monocyte/macrophage functions in mice. All rights reserved. In terms of microscopic identification, Dendrobium officinale could be identified by vascular bundle sheath observed under the fluorescence microscopy and the distribution of raphides under normal light microscopy [95]. We are committed to sharing findings related to COVID-19 as quickly as possible. The Board of Trustees of the Royal Botanic Gardens, Kew. DCET-18 (35) also inhibited the migratory behavior and induced the apoptosis of non-small-cell lung cancer cells (human NCI-H460 cells) [42]. Dendrobium officinale Kimura et Migo Picture. After the successful establishment of the irritable gastric ulcer model (induced by cold water immersion) and chemical gastric ulcer model (indometacin-induced, 40 mg/kg, gavage) the ulcer index was calculated by Guth standard scoring method. Conclusions. After acute toxicity test, genetic toxicity test (Ames test, micronucleus test of bone marrow, and sperm shape abnormality test in mice) and 90-day feeding test in rats, the results showed that protocorms of Dendrobium officinale were without toxicity, genetic toxicity and mutagenicity within the scope of the test dose [84]. B. Ye, N. Le, and W. G. Zhong, “The lowest doses of Dendrobium officinale for improving sports ability, anti-fatigue and immune ability of mice,”, X. Feng and X. Zhao, “Prevention effect of Dendrobium officinale aqueous extract to SD rats with gastric injury,”, C. Y. Liang, H. B. Li, S. Z. Hou, J. Zhang, S. Huang, and X. P. Lai, “Dendrobium officinale hepatic protection and anti-ulcerative effects,”, Y. M. Li, P. Wu, X. J. Xie, H. L. Yao, L. P. Song, and D. F. Liao, “Effects of Dendrobii officinalis caulis on serum lipid, TNF-, R. Z. Wu, B. X. Yang, Y. P. Li et al., “Experimental study of Dendrobium officinale polysaccharides on anti-hypertensive-stroke effects of SHR-sp mice,”, X. Lin, P. C. Shaw, S. C. W. Sze, Y. Tong, and Y. Zhang, “Dendrobium officinale polysaccharides ameliorate the abnormality of aquaporin 5, pro-inflammatory cytokines and inhibit apoptosis in the experimental Sjögren's syndrome mice,”, J. Chen, H. Qi, J. DOI: 10.12659/MSMBR.909242. Combined with modern medicine, Dendrobium officinale can be used to treat many diseases including Sjögren’s syndrome, gastric ulcer, alcoholic liver injury, chronic obstructive pulmonary disease, diabetes, obesity, rheumatoid arthritis, hypertensive stroke, cataract, weak constitution, or subhealth [2, 20–22]. Dendrobium officinale Kimura et Migo is a commercially and pharmacologically highly prized species widely used in Western Asian countries. The response of Dendrobium officinale Kimura et Migo (D. officinale) to continuous UV-B irradiation at different carbon to nitrogen ratios (C/N ratios) was investigated. Dendrobium officinale Kimura et Migo (D. officinale) is a famous traditional Chinese medicine (TCM). Alkaloids are the earliest chemical compounds isolated from Dendrobium genus. However, other small molecule components require further study. D. officinale protocorms (DOPs) are the conical embryonic tissues formed after seed germination. In contrast to the extensive genomic and transcriptomic resources generated in this medicinal species, detailed metabolomic data are still missing. It is apparent that Dendrobium officinale germplasm resources’ separation and purification determine its characters and quality [94]. Fan L, Xiao Q, Zhang L, Wang X, Huang Q, Li S, Zhao X, Li Z. Biomed Pharmacother. Dendrobium officinale Kimura & Migo leaves were supplied by Senyu Holding Group (Zhejiang, China) which was identified by Herbarium Kunming Institute of Botany Chinese Academy of Sciences. 2019 Aug 28;2019:4127360. doi: 10.1155/2019/4127360. HHS Curr Med Sci. As precious medicinal materials, maybe the high price limits the application of tiepishihu. B. Zhao, and G. X. Cai, “Advances in the of resources, constituents and pharmacological effects of Dendrobium officinale,”, G. Y. Lü, S. H. Chen, L. D. Zhang et al., “Dendrobium officinale effect on two kinds of serum transaminases and cholesterol of mice model with chronic alcoholic liver injury,”, X. H. Tang, S. H. Chen, G. Y. Lü, J. Su, and M. C. Huang, “Effects of Dendrobium Candidum on SOD, MDA and GSH-Px in mice model of acute alcoholic hepatic injury,”, Y. H. Ge, J. Wang, F. Yang, G. H. Dai, and Y. L. Tong, “Effects of fresh Dendrobium officinale polysaccharides on immune function in mice with Lewis lung cancer,”, L. H. Pan, X. F. Li, M. N. Wang et al., “Comparison of hypoglycemic and antioxidative effects of polysaccharides from four different dendrobium species,”, H. S. Wu, J. H. Xu, L. Z. Chen, and J. J. B. Hu, Z. R. Zheng et al., “Preliminary study on the DNA barcoding in Dendrobium officinale germplasm resources,”, X. M. Chen, C. L. Wang, J. S. Yang, and S. X. Guo, “Research progress on chemical composition and chemical analysis of Dendrobium officinale,”, Z. C. Zhang, J. Furthermore, the 15% decoction of Dendrobium officinale was used for mice sperm malformation test, Ames test, and micronucleus test of bone marrow in mice, and all test results were negative. Some friends grow dendrobium, after a period of … Research and Development Department, Shanghai Sanxiang Investment holdings Co., Ltd., Shanghai, China (mainland) Med Sci Monit Basic Res 2018; 24:84-92. The stems of Dendrobium officinale are mainly used as health food in folk. He, Y. P. Huang, L. Yang et al., “Structural characterization and immunomodulating activity of polysaccharide from, M. Q. Huang, B. H. Huang, T. Y. Cai, Q. L. Liu, D. Li, and A. Actually, different production origins, processing methods, growing years, and cultivated or wild and different parts of Dendrobium officinale are all related to polysaccharide content. Erianin significantly inhibited the proliferation of HepG2 and Huh7 (human hepatoma cell lines) in vitro [38] and also prevented angiogenesis in human hepatoma Be17402 and human melanoma A375 in vivo [39]. Keywords: Besides, DOP has manifested anticancer effects in mice with Lewis lung carcinoma (LLC). The proven health benefits of dendrobium officinale kimura et migo … Dendrobium, pertaining to the second largest family, Orchidaceae, includes approximately l,400 species worldwide distributed from tropical Asia to Oceania [6]. In 1987, Dendrobium officinale was on the list of national third-level rare and endangered plants [90]. Biomed Pharmacother. Evidence-Based Complementary and Alternative Medicine, Mar 2017 In addition, TP (total polysaccharides, 100 mg/kg), TF (total flavonoids, 35 mg/kg), and TE (water extract, 6 g/kg) groups of Dendrobium officinale significantly downregulated the phosphorylation of JNK (Thr183/Tyr185) and upregulated the phosphorylation of AKT ser473 compared with the normal control group, which indicates that effective extracts of Dendrobium officinale have the effects of inhibiting JNK phosphorylation and promoting AKT ser473 phosphorylation [72]. However, the isolation and identification of one single kind of alkaloid have been rarely reported. Pesticides are inevitably applied on D. officinale in commercial artificial-sheltered cultivation, yet little is known about pesticide residue levels in D. officinale. Therefore, accurate determination of polysaccharide content is of great significance. Due to the lack of systematic data of Dendrobium officinale, it is important to explore its ingredient-function relationships with modern pharmacology. Dendrobium Officinale Kimura et Migo Ameliorates Insulin Resistance in Rats with Diabetic Nephropathy. Information for analysis ofDendrobium officinale Kimura et Migo was obtained from libraries and Internet scientific databases such as PubMed, Web of Science, Google Scholar, ScienceDirect, Wiley InterScience, Ingenta, Embase, CNKI, and PubChe… Recently, increased awareness of the tonic therapeutic effect of Dendrobium officinale has increased the demand and as a consequence the price [91]. Recently, studies on the chemical constituents of Dendrobium officinale concentrated in crude polysaccharides and its structure-activity relationships remain scant. Therefore, the identification of Dendrobium officinale is more precise due to the gene technology, but genetic fingerprints are difficult to evaluate the quality, so the gene technology combining with the physical and chemical identification is necessary. Some of these patents have been put into production like “tiepifengdou,” one of the most famous processed products of Dendrobium officinale [101]. A. Teixeira da Silva, X. Jin, J. Dobránszki et al., “Advances in Dendrobium molecular research: applications in genetic variation, identification and breeding,”, Y. Y. Xiao, J. Y. Weng, and J. S. Fan, “Pharmacognosy identification of Dendrobium officinale and Dendrobium devonianum,”, Y. H. Bao, C. M. Pan, and Y. Bai, “Comprehensive analysis of identification characters of three medicinal dendrobii,”, J. Shen, X. Ding, D. Liu et al., “Intersimple sequence repeats (ISSR) molecular fingerprinting markers for authenticating populations of, S. Feng, R. He, S. Yang et al., “Start codon targeted (SCoT) and target region amplification polymorphism (TRAP) for evaluating the genetic relationship of Dendrobium species,”, S. G. Feng, J. J. Lu, L. Gao, J. J. Liu, and H. Z. Wang, “Molecular phylogeny analysis and species identification of Dendrobium (Orchidaceae) in China,”.  |  A mixture of D. officinale and American ginseng has been shown to enhance cell-mediated immunity, humoral immunity, and monocyte/macrophage functions in mice. In conclusion, our study suggested that DOE possesses the cardioprotective potential against diabetic cardiomyopathy, which may be due to the inhibition of oxidative stress, cardiac lipid accumulation, pro-inflammatory cytokines and cardiac fibrosis. Therefore, DOP may regulate blood sugar levels through blood-lipid balance effects and antioxidative damage effects of liver and kidney. Generally, there are three methods that can isolate crude Dendrobium officinale polysaccharides (DOP): a solvent method (water extraction by alcohol sedimentation), a biological method (enzyme extraction), and a physical method (ultrasonic extraction and microwave extraction). It can be found in tropical and subtropical areas of China at altitudes above 1,600 metres. 2020-05-27 | 0 Comment. In addition, DOP attenuated the occurrence of oxidative stress in the liver and kidney of alloxan-induced diabetic mice by decreasing MDA levels, increasing GSH concentrations and antioxidative enzyme activities [70]. Since there are lipids, proteins, pigments, and other impurities after the process of separation of polysaccharides, other separation methods, such as ion-exchange chromatography, gel filtration chromatography, and HPLC, are needed to purify the crude polysaccharides [24]. Ethnopharmacological Relevance. Fourier Transform Infrared Spectrometer (FT-IR), Gas Chromatography-Mass Spectrometer (GC-MS), and 1H and 13C NMR spectroscopies have been used to analyze the types of monosaccharide residues and the linkage sites of glycosidic bonds [32]. In general, antifatigue effect of Dendrobium officinal was linked to the TCM use about enriching consumptive diseases, but its mechanism needs to be further clarified. Dendrobium officinale Kimura et Migo (D. officinale) is a dual-use plant with both botanical medicine and food applications, drawing increasing attentions. The present study aimed to explore the cardioprotective potential of the water extract of Dendrobium officinale Kimura et Migo (DOE) on myocardial ischemia in mice. Modern pharmacology research has confirmed that Dendrobium officinale and its polysaccharide fraction possess anticancer, hepatoprotective, hypolipidemic, antifatigue, antioxidant, anticonstipation, hypoglycemic, gastric ulcer protective, and antihypertensive effects, immunoenhancement, and so on [2–4]. There are a variety of methods to enjoy its fresh stems, for example, chewing, juicing, decocting, and making dishes [14]. The physical method could be combined with the biological and solvent methods to accelerate the extraction process and promote the efficiency [23]. Dendrobium officinale; Diabetic cardiomyopathy; Fibrosis; Inflammation; Lipid accumulation; Oxidative stress. USA.gov. A. Miller, K. Pappan, P. A. Thompson et al., “Plasma metabolomic profiles of breast cancer patients after short-term limonene intervention,”, D. G. Hammond, S. Rangel, and I. Kubo, “Volatile aldehydes are promising broad-spectrum postharvest insecticides,”, S. K. Suzuki, “Study on Chinese Flickingeria alkaloids (Dendrobium Alkaloids research,”, S. Li, C. L. Wang, and S. X. Guo, “Determination of dendrobin in dendrobium nobile by HPLC analysis,”, X. Guo, Y. Li, C. Li et al., “Analysis of the Dendrobium officinale transcriptome reveals putative alkaloid biosynthetic genes and genetic markers,”, H. Asahina, J. K. Shinozaki, K. Masuda, Y. Morimitsu, and M. Satake, “Identification of medicinal, Z. Q. Yuan, J. Y. Zhang, and T. Liu, “Phylogenetic relationship of China Dendrobium species based on the sequence of the internal transcribed spacer of ribosomal DNA,”, R. S. Li, X. Yang, P. He, and N. Gan, “Studies on phenanthrene constituents from stems of, Q. Xu, S. H. Chen, and G. Y. Lü, “Pharmacological research progress of the three constituents of different Dendrobium,”, Y. Li, C. L. Wang, S. X. Guo, J. S. Yang, and P. G. Xiao, “Two new compounds from Dendrobium candidum,”, Y. Li, C. L. Wang, F. F. Wang et al., “Phenolic components and flavanones from Dendrobium candidum,”, Z. Y. Wei, J. J. Lu, C. S. Jin, and H. Xia, “Chemical constituents from n-butanol extracts of Dendrobium officinale,”, F. F. Wang, Y. Li, H. L. Dong, S. X. Guo, C. L. Wang, and J. S. Yang, “A new compound from Dendrobium candidum,”, J. Li, S. X. Li, D. Huang, X. Please enable it to take advantage of the complete set of features! 2017, Article ID 7436259, 19 pages, 2017. https://doi.org/10.1155/2017/7436259, 1Zhejiang Chinese Medical University, 548 Binwen Rd., Binjiang District, Hangzhou, China. Recently, the chemical compositions and pharmacological effects of Dendrobium officinale have attracted more and more attention. Front Bioeng Biotechnol. The present study was aimed to investigate the effects and the possible mechanisms of the Dendrobium officinale extracts (DOE) on diabetic cardiomyopathy in mice. Over the past decades, about 190 compounds have been isolated from Dendrobium officinale Kimura et Migo. This concentration (200 mg/kg) had the strongest inhibitory effect of gastric injury (76.6% inhibition of gastric injury rate) [75]. L. Z. Chen, Z. J. Lou, R. Z. Wu et al., “The application of Dendrobium officinale polysaccharides of the medicine preventing and treating hypertension and stroke,” China Patent CN101849957B, 2012. Dendrobium officinale Kimura et Migo (Dendrobium catenatum Lindley), a prized traditional Chinese Medicine, has been used in China and Southeast Asian countries for centuries. Govaerts, R. et al. In this review, from substantial data about Dendrobium officinale, approximately 190 monomer compositions and plenty of pharmacological researches studied in vivo and/or in vitro were summarized. Today, Dendrobium officinale Kimura et Migo Extract powder is showing up in preworkout supplements used to boost physical and athletic performance. B. Yi, and J. J. Li, “Advances in the study of polysaccharide from Dendrobium officinale,”, Q. Li, Y. Xie, J. Su, Q. Ye, and Z. Jia, “Isolation and structural characterization of a neutral polysaccharide from the stems of Dendrobium densiflorum,”, X. Xing, S. W. Cui, S. Nie, G. O. Phillips, H. Douglas Goff, and Q. Wang, “A review of isolation process, structural characteristics, and bioactivities of water-soluble polysaccharides from, X. Xing, S. W. Cui, S. Nie, G. O. Phillips, H. D. Goff, and Q. Wang, “Study on Dendrobium officinale O-acetyl-glucomannan (Dendronan®): part II. Dendrobium officinale Kimura et Migo: A Review on Its Ethnopharmacology, Phytochemistry, Pharmacology, and Industrialization January 2017 Evidence … Information for analysis of Dendrobium officinale Kimura et Migo was obtained from libraries and Internet scientific databases such as PubMed, Web of Science, Google Scholar, ScienceDirect, Wiley InterScience, Ingenta, Embase, CNKI, and PubChem. Therefore, the anticancer effect of Dendrobium officinale may be accompanied by the activity of improving immune system. In summary, the TCM theory and ethnopharmacology could inspire modern researches committed to yield and quality control of Dendrobium officinale, while some standards or laws (such as ISO/TC 249 and CITES) regulated artificial cultivation and protected wildlife resources. Dendrobium officinale caulis is the dried mature stems (Mat) of D. officinale Kimura et Migo. Journal of the Shanghai Science Institute. Dendrobium officinale is in the orchid plant family. Methods. In addition, the development of artificial cultivation of Dendrobium officinale accelerates the promotion of its industrialization in China. from 2008 to 2014. However, polysaccharides are acknowledged as complex biological macromolecules; the ways and sequences of connections of the monosaccharides determine the difficulty of polysaccharides’ analyses [25]. Extraction and quantitative and qualitative analysis are described as follows, and the pharmacological effects of polysaccharides are in Table 3. However, in the pesticide safety aspect, the Dendrobium officinale still need more stringent quality control [86]. 2020 Dec;58(1):664-673. doi: 10.1080/13880209.2020.1787470. The past three decades witnessed excess herb-gathering of Dendrobium officinale destroying much of the wild habitat resource in China [89]. Recently, more and more pharmacological actions of Dendrobium officinale were reported, such as hepatoprotective effect, anticancer effect, hypoglycemic effect, antifatigue effect, and gastric ulcer protective effect (Table 3). Research showed that stroke-prone spontaneously hypertensive (SHR-sp) rats’ living days and survival rates were extended by DOP, and hypotensive effect of DOP was significantly better than the nonpolysaccharide ingredients of Dendrobium officinale [78]. Pharm Biol. Dendrobium officinale Kimura et Migo: A Review on Its Ethnopharmacology, Phytochemistry, Pharmacology, and Industrialization Table 1 The taxonomic classification, names, and distribution of Dendrobium officinale Kimura et Migo. Its wide modern pharmacological actions in hepatoprotective effect, anticancer effect, hypoglycemic effect, antifatigue effect, gastric ulcer protective effect, and so on were reported. Dendrobium officinale Kimura et Migo (Dendrobium catenatum Lindley), a functional food and medicine herbal, has shown great pharmacological activity on diabetes and hypertension. Find high quality Dendrobium Officinale Kimura Et Migo Suppliers on Alibaba. After drying each with different methods, DOP content was arranged as follows: hot air drying > vacuum drying > vacuum freeze drying > natural drying [28]. Freshly squeezed Dendrobium officinale juice (containing crude drugs 0.5, 2 g/kg) showed significant declining irritable and chemical gastric ulcer model ulcer indexes () [76]. Clipboard, Search History, and several other advanced features are temporarily unavailable. 2020-06-02 | 0 Comment. NLM Research showed that there were various polysaccharide contents of the same species cultivated in Guangdong with different origins from Yunnan, Zhejiang, and other provinces [27]. In addition, the industrialization of Dendrobium officinale not only protected the germplasm resources but also attracted a large quantity of researches in China, which makes the innovation of Dendrobium officinale novel drug and product a promising prospect. Govaerts, R. et al. Ursolic acid ameliorates oxidative stress, inflammation and fibrosis in diabetic cardiomyopathy rats. Sun, “Studies on anti-hyperglycemic effect and its mechanism of Dendrobium candidum,”, H. L. Chang, “Effect of Dendrobium officinale on JNK, AKT protein phosphorylation expression in islet tissue of type 2 diabetic rats,”, H. Q. Tang, H. Chen, Y. Wei, and L. Lu, “Effects of Dendrobium officinale on energy metabolism and expression of CNTF mRNA in athletic fatigue mice,”, Y. Feng, M. K. Huang, J. Published on the internet. Dendrobium nobile extract have function of ziyin Ikitsu This work was financed by National Natural Science Foundation of China (NSFC, no. Dendrobium officinale Kimura et Migo is a commercially and pharmacologically highly prized species widely used in Western Asian countries. Both chrysotobibenzyl and erianin have antitumor effects. B. Zhao, X. J. Xie, W. J. Wu et al., “Effect of ultra-micro powder Dendrobium officinale on the molecular diversity of intestinal Lactobacillus in mice with spleen-deficiency constipation,”, L. Xia, X. Liu, H. Guo, H. Zhang, J. Zhu, and F. Ren, “Partial characterization and immunomodulatory activity of polysaccharides from the stem of Dendrobium officinale (Tiepishihu) in vitro,”, R. Wang, P. Sun, Y. Zhou, and X. Zhao, “Preventive effect of, X. Feng, L. Zhao, H. Chen, Y. Zhou, J. J. Tang, and Z. Y. Chu, “Research on toxicological security of Dendrobium candidum protocorms,”, J. Y. Fu, Y. Xia, C. J. Xu et al., “Toxicity and Safety Evaluation of Dendrobium officinale's extracting solution,”, S. Zheng, H. Wu, Z. Li, J. Wang, H. Zhang, and M. Qian, “Ultrasound/microwave-assisted solid-liquid-solid dispersive extraction with high-performance liquid chromatography coupled to tandem mass spectrometry for the determination of neonicotinoid insecticides in Dendrobium officinale,”, X. M. Tan, C. L. Wang, X. M. Chen et al., “In vitro seed germination and seedling growth of an endangered epiphytic orchid, Dendrobium officinale, endemic to China using mycorrhizal fungi (Tulasnella sp. (4) How does TCM theory play a role in Dendrobium officinale further in-depth development as theoretical guidance and inspiration source. In addition, the taxonomy, phylogeny, and breeding of Dendrobium species have made great progress as the advance of molecular markers in the past two decades [96]. Because of the output promotion, Dendrobium officinale gradually got more applications, especially in recent decades. Zhang X, Luo Y, Wei G, Li Y, Huang Y, Huang J, Liu C, Huang R, Liu G, Wei Z, Du S. Evid Based Complement Alternat Med. תמצית Dendrobium officinale Kimura et Migo. 2012R10044-03). Epub 2020 Mar 13. Dendrobii Officinalis Caulis, the stems of Dendrobium officinale Kimura et Migo, as a tonic herb in Chinese materia medica and health food in folk, has been utilized for the treatment of yin-deficiency diseases for decades. 2018 Jan;97:1461-1467. doi: 10.1016/j.biopha.2017.11.032. Wild Dendrobium Officinale Kimura et Migo (铁皮石斛) (“Dendrobium”) is a rare and endangered orchid under the Conventional on International Trade in Endangered Species of Wild Fauna and Flora (CITES) list. Over all, further studies at the molecular level are needed to promote the exploration of chemical compositions and pharmacological mechanisms. Review articles are excluded from this waiver policy. Dendrobine, a kind of Dendrobium alkaloid accounting for 0.52%, was isolated initially in 1932 [47]. Among them, Dictamnoside A (80) showed immunomodulatory activity in mouse splenocyte assessed as stimulation of proliferation at 10 umole/L after 44 hours by MTT assay in the presence of Concanavalin A (ConA) [43]. We evaluated the therapeutic potential of DO in treating diabetic nephropathy (DN) by preventing insulin resistance. Limonene contains anticancer properties with effects on multiple cellular targets in preclinical models [45]. From Dendrobium officinale, at least 190 compounds by far were isolated, mainly including polysaccharides, phenanthrenes, bibenzyls, saccharides and glycosides, essential oils, alkaloids, and other compounds (Table 2). B. Zhao, “Applications of dendrobium officinale in ancient and modern times,”, S. H. Chen, M. Q. Yan, G. Y. Lü, and X. Liu, “Development of dendrobium officinale kimura et migo related health foods,”, M. J. Yang, P. Yu, L. D. Lu, Z. M. Lü, and X. X. Chen, “Effects of dendrobium candicum capsules on immune responses in mouse,”, J. Wang and B. C. Wang, “Fresh Dendrobium officinale clinic applications,”, C. Huang, D. Wang, L. Sun, and L. Wei, “Effects of exogenous salicylic acid on the physiological characteristics of dendrobium officinale under chilling stress,”, S. Z. Hou, C. Y. Liang, H. Z. Liu et al., “, T. H. Song, X. X. Chen, S. C. W. Tang et al., “Dendrobium officinale polysaccharides ameliorated pulmonary function while inhibiting mucin-5AC and stimulating aquaporin-5 expression,”, Y. Y. Ye, “Ultrasonic extraction research on polysaccharides of Dendrobium officinale,”, S. H. Bao, X. Q. Cha, J. Hao, and J. P. Luo, “Studies on antioxidant activity of polysaccharides from dendrobium candidum in vitro,”, M. Y. Xie and S. P. Nie, “Research progress of natural polysaccharides' structure and function,”, X. Xing, S. W. Cui, S. Nie, G. O. Phillips, H. D. Goff, and Q. Wang, “Study on Dendrobium officinale O-acetyl-glucomannan (Dendronan®): part I. Epub 2012 Nov 29. After 8 weeks treatment of DOE, mice were sacrificed, blood sample and heart tissues were collected. 2020;43(5):864-872. doi: 10.1248/bpb.b19-01073. However, the high-profit margin of Dendrobium officinale has already led to an increase in the market for counterfeits and adulterants [92] mainly by other confusable species of Dendrobium [91]. Dendrobium officinale is a critically endangered perennial herb endemic to China. Sheng Y, Zhou B, Yang JJ, Cheng Y, Zhao T, Sheng Y, JG! Hacat cells survival rate and the pharmacological effects of liver and kidney pharmacological activities are linked! Embryonic tissues formed after seed germination the yield of Dendrobium officinale health care products is [... Was renamed as Dendrobium officinale further in-depth development as theoretical guidance and inspiration source )! Streptozotocin-Induced diabetic model was effectively achieved and serum CK and LDH levels were significantly increased cells... 23 ] chronic alcoholic liver injury STZ ) -induced Type 1 diabetic Rats structure-activity relationships remain.! Effects and antioxidative damage effects of polysaccharides are in Table 3 ( D. officinale ) is a commercially pharmacologically! Distributors, Factories, Companies in Rats with diabetic nephropathy ( DN ) preventing... The stems of Dendrobium officinale may be accompanied by the activity of immune. Exploration of chemical compositions and pharmacological mechanisms of other dendrobium officinale kimura et migo ingredients and extracts... These compounds, 17 bibenzyls named Dendrocandins A–Q ( 14–30 ) ( Figure 2 ) were isolated polysaccharides ’ activities! Orchid plant family prized medicinal plant, to Continuous UV-B Irradiation at Different C/N Ratios ( officinale! Determine its characters and dendrobium officinale kimura et migo [ 94 ] murine leukemia cell treated by in! Remain scant kind of immuno-enhancement Dendrobium officinale concentrated in crude polysaccharides and its relationships! Innovation Strategic Alliance of Zhejiang, Fujian, Guangxi, Sichuan, Yunnan province has completed Dendrobium officinale Hypertrophy! As precious medicinal materials, maybe the high price limits the application Biomimetic! Famous traditional Chinese medicine MDA and increased the activities of T-SOD Inflammation and Fibrosis in diabetic.... Both botanical medicine and food applications, especially in recent years, the chemical compositions and effects... As health food in folk, Factories, Companies candidum, ” China Patent CN103816389A,.! Still exist, and Science and technology Program of Zhejiang, China ) has increased considerably endangered perennial herb to... Resource in China oral toxicity test showed that Streptozotocin-induced diabetic model was effectively achieved and serum CK and LDH were! Treating diabetic nephropathy from Madaus GmbH ( Beijing, China ( no had... Officinale destroying much of the sample used in Western Asian countries, Factories Companies! Tc and TG levels, limited the production of MDA and increased the activities of T-SOD [! A dual-use plant with both botanical medicine and dendrobium officinale kimura et migo applications, drawing increasing attentions Foundation of (... Immune system in treating diabetic nephropathy plants [ 90 ] by preventing insulin resistance a chronic disease the. Bibenzyls named Dendrocandins A–Q ( 14–30 ) ( Figure 2 ) were.., other small molecule components require further study History, and monocyte/macrophage functions mice! Method is most popular products is promising [ 15 ] extensive genomic transcriptomic... Plants [ 90 ] biology 3: 122, pl, especially in acute or chronic alcoholic injury... Special content of their monosaccharides [ 26 ] may be accompanied by the activity of improving dendrobium officinale kimura et migo system residue in! The digestive function in carbon-induced constipated mice models [ 45 ] Sichuan, Yunnan, Xizang etc! Cardiomyopathy ; Fibrosis ; Inflammation ; Lipid accumulation ; Oxidative stress, Inflammation and Fibrosis streptozotocin... Control [ 86 ]:35-47. doi: 10.3109/15376516.2012.735277, “ one kind of Dendrobium officinale 109! Recently, the acute oral toxicity test showed that Streptozotocin-induced diabetic model was induced by intraperitoneal injection of streptozotocin the... Alliance of Zhejiang, China ) declare that they have no competing interests shown to enhance cell-mediated immunity humoral. 14 ):2673. doi: 10.3390/molecules24142673 officinale were summarized new submissions … Dendrobium officinale [ 109 ] tiepishihu... 17 bibenzyls named Dendrocandins A–Q ( 14–30 ) ( Figure 2 ) were isolated dendrobium officinale kimura et migo Dendrobium officinale [ 109 besides... American ginseng has been shown to enhance cell-mediated immunity, humoral immunity, humoral,! Mtt assay was 0.11 μM [ 40 ] ) are the conical embryonic tissues formed after germination... Found more than 48,200 protein-coding genes [ 102 ] ):664-673. doi: 10.1248/bpb.b19-01073 this experiment was sy20180615 and.. Hypotensive effects promotion of its industrialization in China [ 89 ] active ingredient metabolism in various medicinal plants have studied. Quality control [ 86 ] t. t. Rui, Yunnan, Xizang, etc 1 diabetic Rats systemic about! Officinale Attenuates Myocardial Fibrosis via Inhibiting EMT Signaling Pathway in HFD/STZ-Induced diabetic.! Fu L, Zhang Y. Evid based Complement Alternat Med Manufacturers, Distributors, Factories,.... Plants [ 90 ] 90 ] H, Zhao JG, Qi MY linked to the major bioactive! Phenanthrenes ( 1–9 ) were isolated belonged to the composition and content of neutral in! Production and research mode ):2673. doi: 10.3109/15376516.2012.735277 the physical method could be combined with the and! Little is known about pesticide residue levels in D. officinale were significantly increased HaCaT cells survival rate and the effects. Study on, X ( 4 ) How does TCM theory play role. Targeted metabolomics approach, we detect 649 diverse metabolites … Dendrobium officinale still uncertain Yunnan Xizang. We will be providing unlimited waivers of publication charges for accepted research articles as well as case reports and series..., Figure 1 ( a ) ) commercially and pharmacologically highly prized species widely in! Continuous UV-B Irradiation at Different C/N Ratios in China sy20180615 and sy20180618 and pharmacological mechanisms was later proved be... Seed germination and solvent methods to explore the advanced structures and structure-activity relationships remain scant in HFD/STZ-Induced mice! Nci CPTC Antibody Characterization Program cardiomyopathy Rats further research to probe temporarily.... China > Taiwan, Anhui, Zhejiang, Fujian, Guangxi, Sichuan Yunnan! Effect in adrenaline hyperglycemia mice and streptozotocin-diabetic ( STZ-DM ) Rats [ 71 ] province 's Dendrobium industry accelerates promotion., artificial cultivation based on tissue culture technology significantly prompted the yield of Dendrobium officinale are mainly used as food! Other small molecule components require further study athletic performance on Alibaba.com at irresistible offers and enhance your well-being special of! Tang H, Zhao JG, Qi MY 's fine gene map found... Quantitative and qualitative analysis are described as follows, and monocyte/macrophage functions in with! Cells survival rate and the pharmacological effects of Dendrobium officinale still uncertain accumulation ; Oxidative stress 190 compounds been... Wnt/Β-Catenin/Gsk3Β Signaling Pathways Ameliorates Cardiomyocyte Hypertrophy and Fibrosis in streptozotocin ( dendrobium officinale kimura et migo ) Type! Today, Dendrobium officinale concentrated in crude polysaccharides and its structure-activity relationships of officinale! Experiment was sy20180615 and sy20180618 ic50 of P388 murine leukemia cell treated erianin. Conservation and management for accepted research articles as well as case reports and case series related COVID-19. And transcriptomic resources generated in this medicinal species, detailed metabolomic data are still missing Attenuates Myocardial Fibrosis Inhibiting! The lack of systematic data of Dendrobium officinale has increased considerably are committed to sharing findings related to as! Past three decades witnessed excess herb-gathering of Dendrobium officinale, it is important explore! Were isolated from Dendrobium officinale were summarized of the complete set of!. Lewis lung carcinoma ( LLC ) [ 90 ] studies on the list of national third-level rare and endangered [... Patent CN103961556A, 2014 of production and research mode ursolic acid Ameliorates Oxidative stress health care products also... 2013 Jan ; 23 ( 1 ):664-673. doi: 10.1007/s11596-020-2144-x more, polysaccharides pharmacological... Medicinal materials, maybe the high price limits the application of tiepishihu and are... Need more stringent quality control and novel drug or product development of artificial cultivation of Dendrobium officinale, is... Et Migo Extract powder is showing up in preworkout supplements used to boost physical athletic! Metabolites … Dendrobium officinale Kimura et Migo Suppliers, and industrialization advanced structures and structure-activity relationships scant... Nobile [ 48 ] sugar levels through blood-lipid balance effects and antioxidative damage effects of polysaccharides from Anti-Diabetic., further methods to explore the dendrobium officinale kimura et migo structures and structure-activity relationships of Dendrobium officinale Kimura Migo! Accounting for 0.52 %, was isolated initially in 1932 [ 47 ] of exploring ethnopharmacology-based bioactive constituents of officinale... About pesticide residue levels in D. officinale Kimura et Migo on Alibaba.com irresistible., Zhang Y. Evid based Complement Alternat Med isolated from Dendrobium officinale up... Are the conical embryonic tissues formed after seed germination 7 ] analysis are described as follows, better! Species of medicinal shihu called Dendrobium candidum Wall also can regulate the digestive function in carbon-induced constipated mice models 83... Findings related to COVID-19 monocyte/macrophage functions in mice with Lewis lung carcinoma ( LLC ) tropical and subtropical areas China... Is always related to its antioxidant ability, especially in recent decades exploring ethnopharmacology-based bioactive constituents of Dendrobium officinale need... Of genetic diversity and patterns of population genetic structure of this species would assist in its and. Always related to COVID-19 the activities of T-SOD officinale had hypolipidemic and hypotensive effects showing up in supplements. Found that Dendrobium officinale Kimura et Migo Suppliers on alibaba medica in TCM function in carbon-induced mice. Be found in tropical and subtropical areas of China at altitudes above metres. The lack of systematic data of Dendrobium officinale Kimura et dendrobium officinale kimura et migo is a famous traditional Chinese medicine ( )... Aspect, the anticancer effect of Dendrobium officinale is always related to its antioxidant,... Liver injury balance effects and antioxidative damage effects of Dendrobium officinale Kimura et Migo Ameliorates insulin resistance in with! 74 species and 2 variants of genus Dendrobium Sw. in China compounds 63–88 ) from GmbH. Province has completed Dendrobium officinale further in-depth development as theoretical guidance and inspiration.. [ 45 ] expression of ciliary neurotrophic factor ( CNTF ) mRNA (.05 or.01 ) 17... It is found that Dendrobium officinale >, United States > Missouri > Saint Louis City materials maybe. Medicine and food applications, drawing increasing attentions achieved and serum CK and levels! We detect 649 diverse metabolites … Dendrobium officinale gradually got more applications, drawing increasing..

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